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This book identifies 50 key scientific articles in the field of breast disease and surgery, examining their importance and impact. A valuable reference to the established surgeon, breast surgery residents and trainees.
There has been an exponential increase in the volume and quality of published research relating to breast disease over the past decades. This book identifies the 50 key scientific articles in the field of breast disease and breast surgery and examines their importance and impact on current clinical care. Among thousands of articles, a small fraction are truly 'game changing'. Such studies form the foundations of breast surgery today, and the selection of papers within this book provide the 50 landmark papers every 21st-century breast surgeon needs to know. A commentary to each carefully selected paper explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area. A valuable reference not only to the established surgeon, but also to breast surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of breast disease and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research.
This book provides an expert perspective, from some of the world’s leading surgeons, on the papers that have had the greatest impact in the field of thyroid and parathyroid surgery over the past decade. The broad range of topics covered will enable the reader to understand how recent research developments have led to changes in current thyroid and parathyroid surgical practice and represents an excellent resource for trainees at all levels preparing for specialty examinations. This book contains: Concise review and analysis of key papers by expert clinicians with each chapter focused on the most important aspects of the surgical management of thyroid and parathyroid disease Essential reading for students, residents, fellows and surgeons studying for their professional exams or wanting an update on the current thyroid and parathyroid surgery literature Critical distillation of the diverse and expanding research over a broad range of topics from this field that includes investigation and management of benign and malignant thyroid disease, primary, secondary and tertiary hyperparathyroidism, thyroid and parathyroid surgery and surgical complications Expert analysis of the key contemporary papers and topics underlying the practice of endocrine neck surgery for general surgeons, otolaryngologists, head and neck surgeons, endocrine surgeons, trainees and other healthcare professionals
There has been an exponential increase in the volume and quality of published research relating to spine care over the last several decades. Among thousands of articles, a small fraction has been shown to be truly "game changing," forcing the entire field to pause and take notice. These landmark studies may describe a new procedure or surgical approach, evaluate the relative effects of known treatments or techniques, introduce a new classification system, or provide new insights into natural history or disease prognosis. Such studies form the foundations of spine surgery today.This book will be a useful reference not only to the established spine surgeon, but also to neurosurgery and orthopedic residents, as well as to spine surgery fellows as they continue to fortify their knowledge surrounding spinal disorders. Further, this will no doubt serve as a useful evidence-based resource for trainees studying for professional examinations and perhaps most importantly challenge and inspire clinicians to produce high-quality impactful research.
There has been an exponential increase in the volume and quality of published research relating to colorectal disease over the last decades. This book identifies the 50 key scientific articles in the field of colorectal disease and colorectal surgery and through expert reflections and editorial perspectives explains why these papers are important. Influential contributors who have shaped the practice of modern Colorectal Surgery comment on the Landmark Papers that have shaped and defined the specialty. Among thousands of articles, a small fraction are truly “game changing.” Such studies form the foundations of colorectal surgery today and the selection of papers within this book provide the 50 landmark papers every 21st-century colorectal surgeon needs to know. A commentary to each carefully selected paper explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area. A valuable reference not only to the established surgeon, but also to colorectal surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of colorectal disease and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research.
50 Studies Every Surgeon Should Know presents key studies that have shaped the practice of surgery. Selected using a rigorous methodology, the studies cover topics including: vascular, colorectal, bariatric, abdominal, hernial, and endocrine surgery, surgical outcomes, surgical oncology, trauma and surgical critical care, and studies of historical interest. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.
Landmark Papers in General Surgery will give surgeons, surgical trainees and other healthcare professionals an expert appraisal of key papers, and fast access to the evidence base behind current clinical practice in General Surgery. Each chapter draws together a fascinating selection of the most important clinical trials across every subspecialty within General Surgery, as selected and appraised by a panel of experts. Organized according to a common format, each discussion offers a clear structure by which to appraise the medical literature. Following a background summary of each trial, experts discuss the impact of the research and critique the methods used, giving the reader rapid understanding of the paper's place within the wider field of research. This emphasis on the tools of critical appraisal is enhanced by an introductory chapter equipping the reader with the skills required to knowledgeably appraise a research paper. For clinicians needing to keep abreast of the vast scope of medical research, this book will prove an interesting and timesaving resource, but it will also appeal to allied health professionals keen to improve the depth of their understanding of surgery. By bringing together the evidence base with expert guidance on critical appraisal, higher surgical trainees preparing for the academic and specialty sections of the FRCS exit examination will also find the text invaluable as a means of consolidating and nuancing their knowledge.
The exponential growth in the number of research papers published in recent decades can make it difficult to identify the key papers that have truly made a difference in the practice of oral and maxillofacial surgery. This book provides readers with a concise reference source for the key papers that underpin contemporary surgical practice in oral and maxillofacial surgery. Covering all aspects of the specialty, the content will help both trainees and specialists to understand the scientific developments and pioneering surgeries that allow us to practice as we currently do. It is essential revision material for those sitting for specialist examinations in oral and maxillofacial surgery. + Presents 50 key research studies on surgery along with full analysis + Additional commentaries from the original authors, experts or editors - providing a valuable perspective on why the study is important + Constitutes essential reading for trainees, residents and fellows, and surgeons studying for professional examinations + Distills all the literature into a compact guide on the must-know scientific articles About the Editors Niall MH McLeod FRCS (OMFS), FDS, MRCS Consultant Oral & Maxillofacial Surgeon, The Royal London and Whipps Cross Hospitals, London, UK Peter A Brennan MD, PhD, FRCS, FRCSI, FDS Consultant Maxillofacial Surgeon and Professor of Surgery, Queen Alexandra Hospital, Portsmouth, UK
An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.
Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.