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The pioneering surgeon Dr. Denton Cooley performed his first human heart transplant in 1968 and astounded the world in 1969 by conducting the first successful implantation of a totally artificial heart in a human being. Over the course of his career, Cooley and his associates performed thousands of open-heart operations and pioneered the use of new surgical procedures. Of all his achievements, however, Cooley was most proud of the Texas Heart Institute, which he founded in 1962 with a mission to use education, research, and improved patient care to decrease the devastating effects of cardiovascular disease. In 100,000 Hearts, Cooley tells about his childhood in Houston, his education at the University of Texas, his medical-school training at the University of Texas Medical Branch in Galveston and Johns Hopkins, and his service in the Army Medical Corps. While at Johns Hopkins, Cooley assisted in a groundbreaking operation to correct an infant’s congenital heart defect, which inspired him to specialize in heart surgery. Cooley’s detailed descriptions of working in the operating room at crucial points in medical history offer a fascinating perspective on the distance medical science traveled in just a few decades.
In 2008, the University of Pittsburgh Medical Centers (UPMC) hoisted its logo atop the U.S. Steel Building in downtown Pittsburgh, symbolically declaring that the era of big steel had been replaced by the era of big medicine for this once industrial city. More than 1,200 miles to the south, a similar sense of optimism pervaded the public discourse around the relationship between health care and the future of Houston's economy. While traditional Texas industries like oil and natural gas still played a critical role, the presence of the massive Texas Medical Center, billed as "the largest medical complex in the world," had helped to rebrand the city as a site for biomedical innovation and ensured its stability during the financial crisis of the mid-2000s. Taking Pittsburgh and Houston as case studies, The Medical Metropolis offers the first comparative, historical account of how big medicine transformed American cities in the postindustrial era. Andrew T. Simpson explores how the hospital-civic relationship, in which medical centers embraced a business-oriented model, remade the deindustrialized city into the "medical metropolis." From the 1940s to the present, the changing business of American health care reshaped American cities into sites for cutting-edge biomedical and clinical research, medical education, and innovative health business practices. This transformation relied on local policy and economic decisions as well as broad and homogenizing national forces, including HMOs, biotechnology programs, and hospital privatization. Today, the medical metropolis is considered by some as a triumph of innovation and revitalization and by others as a symbol of the excesses of capitalism and the inequality still pervading American society.
Fighting heart disease with machines and devices-- Multiple approaches to building artificial hearts : technological optimism and political support in the early years -- Dispute and disappointment : heart transplantation and total artificial heart implant cases in the 1960s -- Technology and risk : nuclear-powered artificial hearts and medical device regulation -- Media spotlight : the Utah total artificial heart -- Clinical and commercial rewards : ventricular assist devices -- Securing a place : therapeutic clout and second-generation VADs -- Artificial hearts in the 21st century
This absorbing and poignant book is not merely the story of one writer's flawed heart. It is a history of cardiac medicine, a candid personal journey, and a profound reflection on mortality. Born in 1966 with a congenital heart defect known as the tetralogy of Fallot, Gabriel Brownstein entered the world just as doctors were learning to operate on conditions like his. He received a life-saving surgery at five years old, and since then has ridden wave after wave of medical innovation, a series of interventions that have kept his heart beating. The Open Heart Club is both a memoir of a life on the edge of medicine's reach and a history of the remarkable people who have made such a life possible. It begins with the visionary anatomists of the seventeenth century, tells the stories of the doctors (all women) who invented pediatric cardiology, and includes the lives of patients and physicians struggling to understand the complexities of the human heart. The Open Heart Club is a riveting work of compassionate storytelling, a journey into the dark hinterlands between sickness and health lit by bright moments of humor and inspiration.
A deeply compelling biography of the pioneering children’s heart doctor Helen Taussig, who helped start heart surgery and became a global force against preventable suffering. In A Heart Afire, Patricia Meisol renders a moving portrait of the indomitable pediatrician and global patient activist Helen Taussig (1898–1986), who famously gathered and publicized evidence linking thalidomide to birth defects, leading to US drug safety laws. Taussig also developed the Blalock-Taussig shunt (along with Alfred Blalock) for infants with congenital heart defects. Spanning Taussig’s childhood in Boston, her struggle with dyslexia, her progressive hearing loss, her research contributions, and the founding of her own fledgling children’s heart clinic, this book chronicles Taussig’s ambition, tenacity, and formidable work ethic. As Meisol shows, Taussig not only saved lives, but also set a bold precedent for other women doctors in the twentieth century, who were largely excluded from medicine. Meticulously researched and intimately told, A Heart Afire is unique in its use of a fifty-year-long campaign by Taussig’s followers for a worthy memorial portrait and shows how views of women doctors have evolved. Meisol reveals Taussig as an authentic American hero, one who embodies the Emersonian ethic of developing oneself, following the processes of nature, and serving the public. A fiercely independent thinker, Taussig infused herself and her ideas into the medical culture, paving the way not only for other professional women but also for patients then and now to advocate for themselves. Offering an indispensable look at health care as a universal human right, A Heart Afire is a beacon and a blueprint for creating a more just and compassionate world of medicine.
The beginning of cardiac surgery is generally considered to be the successful repair of a wound of the heart that took place on the 7th of September 1896 in Frankfurt am Main. This operation put an end to the widespread belief that nature had set the heart beyond the limits of surgery. The successive development of heart surgery moved together with other advances that were rapidly taking place in various fields of medicine and surgery and which, already in the first half of the 20th century, had allowed surgical pioneers to successfully correct a number of congenital and acquired heart diseases by adopting closed-heart techniques. Undoubtedly, the most notable progress in the history of cardiac surgery took place between the second half of the 1950s and the end of the 1960s with the introduction of extra-corporeal circulation that allowed surgeons to perform interventions under direct vision within the bloodless heart chambers. This fundamental technological innovation fostered the development of surgical procedures that are still adopted to this day. Among these that must be mentioned are the correction of complex congenital heart diseases, the designing and creation of implantable prosthetic heart valves, the introduction of coronary artery surgery, the repair of severe diseases of the aorta, the commencement of heart transplantation, and the first implantation of an artificial heart. This book narrates these fascinating and sometimes dramatic events, as well as detailing some of the greatest pioneers of cardiac surgery.
Cardiac Cowboys is the dramatic story of five deeply flawed geniuses who together—and in competition with each other—invented open-heart surgery against all conventional medical wisdom and saved millions of lives. A decade after World War II, there was still no such thing as open-heart surgery, and yet half a million Americans were dying from heart disease every year. One in a hundred children would suffer and die from congenital heart disease as well, and doctors did little other than predict their deaths. After the first daring operation in 1954 and through the next three decades, five heroic surgeons braved the scorn of their peers, withstood fierce desperation, and faced possible death in order to devise procedures that would save overwhelming numbers of those doomed children and provide hope for a new life to all manner of heart-failing individuals. Devising and mastering heart transplants and bypass surgery, they invented artificial heart valves, the lifesaving pacemaker, and worked toward the holy grail of an artificial heart as their private and professional lives imploded. The story of the Cardiac Cowboys, their outsized personalities, and often self-destructive behavior is a saga more thrilling and exhilarating than fiction.
It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.
This book provides a comprehensive overview of mechanical circulatory support of the failing heart in adults and children. The book uniquely combines engineering knowledge and the clinician’s perspective into a single resource, while also providing insights into current and future development of mechanical circulatory support technology, such as ventricular assist devices, the total artificial heart and catheter-based technologies for heart failure. Topics featured in this book include: The history of mechanical circulatory device development. Fundamentals of hemodynamics support. Clinical management of mechanical circulatory devices. Surgical implantation techniques. Current limitations of device therapies in advanced heart failure. Advanced and novel devices in the development pipeline. Opportunities for advancement in the field. Mechanical Support for Heart Failure: Current Solutions and New Technologies is a must-have resource for not only physicians, residents, fellows, and medical students in cardiology and cardiac surgery, but also clinical and basic researchers in biomedical engineering with an interest in mechanical circulatory support, heart failure, and new technological applications in medicine.
"We live in a time of change, an era where old men can maintain health but find dignity in frailty. Old Man Country helps readers see and imagine this change for themselves. The book follows the journey of a writer in search of wisdom, as he narrates encounters with twelve distinguished American men over 80 -- including Paul Volcker, the former head of the Federal Reserve, and Denton Cooley, the world's most famous heart surgeon. In these and other intimate conversations, the book explores and honors the particular way that each man faces the challenges of living a good old age"--