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Make a game of learning to count by tens all the way to one hundred-with the added fun of finding one little creature hidden on each page!
"This self-help guide will empower cats to make the 20 minutes they're awake each day the best 20 minutes of their lives"--Provided by publisher.
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love.Who Is Geronimo Stilton?That's me! I run a newspaper, but my true passion is writing tales of adventure. Here on Mouse Island, my books are all best-sellers! What's that? You've never read one? Well, my books are full of fun. They are whisker-licking good stories, and that's a promise!The Case of Curlypaw Cannycat's CastleI was lost in a dark, spooky forest! Until I stumbled upon Curlypaw Cannycat's Castle. The castle was completely empty, or so I thought. But I quickly discovered that it was haunted - by cats! Let me tell you, this was one case where curiosity almost killed the mouse!
Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available
The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. - Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications - Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes - Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation - Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success
Featuring 10 heirloom knitwear patterns for children, this collection celebrates the artistry and craftsmanship of two of the knitting community's most prominent designers. The intricately designed patterns, suitable for children from their toddler years to their preteens, include cardigans and vests, cable pullovers, and adorable dresses. Each pattern provides detailed instructions and easy-to-follow charts, including information about yarn specifications, such as ply, wraps per inch, meters to the gram and kilogram, and yards to the ounce and pound. The exquisite fashion photography of finished garments shows off the creations worked in rich, glowing colors. In addition to patterns, short excerpts from beloved children's books are interspersed throughout.